ActyColl – Advanced Collagen Membranes

In Guided Bone Regeneration (GBR), the membrane has historically been viewed as a mere passive barrier. ActyColl redefines this concept, transitioning from a simple wall to a bioactive partner that actively facilitates the healing process.

1. From Passive Barrier to Bioactive Healing

ActyColl is a new generation of fully resorbable collagen membranes crafted from highly purified equine type I atelocollagen. Unlike traditional membranes that only prevent soft-tissue infiltration, ActyColl actively releases growth factors like TGF-β and BMP-2 to accelerate bone formation and tissue remodeling.

• 100% Bio-Resorbability: Engineered to be fully absorbed by the body, eliminating the trauma and complications of a second surgical procedure.
• Dual-Action Design (ActyColl RS): Features a rough side for optimal graft stability and cell adhesion, paired with a smooth side that acts as a superior soft-tissue barrier.

2. Specialized Clinical Solutions

Regenerative success demands versatility. Beyond membranes, the ActyColl Fleece serves as a high-performance haemostatic sponge, ideal for immediate extraction sockets and precise bleeding control in complex surgical sites.

3. OptyBone + EstRem™: The Perfect Synergy

The true power of regeneration is realized when ActyColl is paired with OptyBone. Powered by patented EstRem™ technology, this partnership ensures maximum biocompatibility and predictable long-term success.

• 99.9% Biocompatibility Rate: Our Esterification Cell-Removal process removes 100% of immunogenic elements while preserving the natural bone architecture.
• Zero Compromise: Maintains native collagen and growth factors, creating the safest xenograft environment ever developed for dental surgery.

The Regenerative Ecosystem:

• ActyColl RS: The gold standard for dual-sided tissue management.
• OptyBone Matrix: Patented technology for natural bone remodeling.
• ActyColl Fleece: Advanced haemostatic support for surgical efficiency.